RNS Number : 7933V

Skyepharma PLC

02 June 2008

For Immediate Release 2 June 2008

SkyePharma PLC ('the Company')

The Company was informed on 02 June 2008 that as a result of transactions on 02 June 2008 by the SkyePharma PLC Share Purchase Plan (an approved all employee share purchase plan) the Trustees of the Plan purchased an additional 20,122 Ordinary Shares of the Company at a price of 7.16 pence per share.

Following these transactions, the Trustees hold on behalf of the Plan, 238,084 Ordinary Shares representing 0.029% of the share capital of the Company. The class of discretionary beneficiaries for whom the Trustees hold such shares consists of employees of the Company, including the following Executive Directors: Frank Condella and Peter Grant.

As a result of these transactions, the following Executive Directors have the following additional interests as a result of their personal participation in the Plan:-

Partnership Shares Matching Shares Total number of

purchased on 02 awarded on 02 June Partnership and

June 2008 at 7.16p 2008 at 7.16p per Matching Shares held

per share share on 02 June 2008

Frank Condella 1747 1747 34,902

Peter Grant 1747 1747 27,530

In accordance with the rules of the Plan these Directors have been awarded Matching Shares on the basis of one Matching Share (Ordinary Share) for each Partnership Share (Ordinary Share).

The beneficial ownership of the Matching Shares will pass to the Directors in three years' time subject to continued employment and the retention of the underlying Partnership Shares.

The execution of the transaction noted above did not involve any of the Company's Directors or any persons discharging managerial responsibility.

This notification relates to transactions notified in accordance with Disclosure and Transparency Rule 3.1.4R(1)(a).

This information is provided by RNS

The company news service from the London Stock Exchange

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